National Chromatography Inco
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Ultimasyil AQ 150Å columns are advanced reversed-phase HPLC columns designed for the separation of polar and hydrophilic compounds in highly aqueous mobile phases. These columns are specifically engineered with C18 ligands and polar endcapping, optimized for 100% aqueous compatibility, while offering a larger 150 Å pore size—ideal for moderately sized biomolecules.
Applications:
Ideal for hydrophilic analytes in highly aqueous mobile phases
Suitable for biomolecules including small peptides, nucleosides, and natural products
Excellent for pharmaceutical analysis, metabolite profiling, and bioanalytical methods
Can be used in gradient or isocratic methods
Advantages:
Prevents stationary phase dewetting (unlike standard C18 columns)
Provides improved retention and peak shape for polar compounds
Increased reproducibility and column lifetime under aqueous conditions
Supports larger analytes due to the 150 Å pore size
