Ultimasyil C18 100 Å is a reversed-phase (RP) HPLC column widely used for method development and routine chromatography. Here are the key details:
1. Silica and Bonding Characteristics
Packed with high-purity, spherical silica gel (99.99% SiO₂) .
The C18 alkyl chains are bonded to the silica and the stationary phase is end-capped, reducing silanol activity and improving peak symmetry .
Offers a surface area of approximately 375 m²/g and carbon loading around 12% .
2. Performance Highlights
Resolution & Retention: The 100 Å pore size provides balanced retention and resolution for a wide array of compounds. It typically requires less organic modifier in the mobile phase compared to smaller pore sizes like 80 Å .
Versatility: Comparable to well-known columns like Kromasil, Hypersil, Phenomenex Luna, Waters Symmetry, or Inertsil—making it an excellent choice for replacing or replicating established methods .
The Ultimasyil C18 100 Å preparative column offers:
High-purity spherical silica (99.99% SiO₂)
End-capped, L1 C18 phase with 12% carbon load
375 m²/g surface area for strong retention and good efficiency
Broad applicability, suitable for replacing many standard columns