National Chromatography Inco
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Hi-Purit™ Cyano 40–75 µm Flash Cartridges are typically used in flash chromatography for purification of organic compounds, particularly in synthetic and medicinal chemistry labs. Here's a breakdown of their common uses and applications:
Primary Uses of Hi-Purit™ Cyano Flash Cartridges:
Normal Phase Flash Chromatography:
The cyano (CN) stationary phase offers intermediate polarity, making it suitable for separating compounds that are difficult to resolve with standard silica.
Reverse Phase Compatibility:
CN phases can sometimes be used in reverse-phase conditions with aqueous-organic mobile phases, offering flexibility depending on compound polarity.
Purification of Complex Mixtures:
Especially useful in combinatorial chemistry, natural product isolation, or drug discovery, where compound libraries need rapid purification.
Separation of Compounds with Similar Structures:
Cyano phases can provide better selectivity for certain functional groups (e.g., ketones, nitriles, and aromatics) than traditional silica.
Improved Peak Shape & Resolution:
Often used when silica gives poor peak shape or when tailing of polar compounds is an issue.
