National Chromatography Inco
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Hi-Purit™ SCX SPE cartridges are solid phase extraction (SPE) cartridges that use strong cation exchange (SCX) sorbents. These are commonly used in sample preparation to selectively retain and purify positively charged compounds (cations), especially in complex matrices.
Typical Uses of Hi-Purit™ SCX SPE Cartridges:
1. Sample Cleanup:
Biological samples (e.g., plasma, serum, urine)
Environmental samples (e.g., wastewater, soil extracts)
Food and beverage matrices
These cartridges help remove matrix interferences and concentrate analytes of interest.
2. Extraction of Basic Compounds:
SCX sorbents are ideal for extracting basic drugs (e.g., amines, alkaloids, peptides, etc.) from biological or pharmaceutical samples.
Commonly used in forensic and clinical toxicology labs.
3. Purification Before LC-MS or GC-MS:
Removing salts, proteins, and other contaminants before analysis improves sensitivity and reproducibility in techniques like LC-MS/MS or GC-MS.
