Hi-Purit™ Si SPE (Solid Phase Extraction) Cartridges are typically used in sample preparation processes for analytical chemistry, especially in the fields of pharmaceuticals, environmental analysis, food safety, and clinical testing. The “Si” in the name refers to silica-based sorbent material, which is commonly used in normal phase SPE.
Common Uses of Hi-Purit™ Si SPE Cartridges:
1. Normal Phase SPE Applications
Silica sorbents are polar, making them ideal for retaining polar compounds from non-polar solvents.
Useful in separating polar analytes from non-polar matrices like oils or organic solvents.
2. Sample Clean-up
Removes matrix interferences before analysis via HPLC, GC, or MS.
Enhances the accuracy and sensitivity of the analysis.
3. Purification of Organic Compounds
Especially in synthetic organic chemistry for purifying reaction mixtures.
Isolates desired polar compounds from non-polar impurities.
4. Separation of Isomers or Related Compounds
Exploits differences in polarity and interaction with the silica surface.
5. Extraction of Acidic or Basic Compounds
Depending on mobile phase pH and compound properties, can selectively extract acidic, basic, or neutral molecules.