Hi-Purit™ CN SPE (Solid Phase Extraction) Cartridges are used for sample preparation in analytical chemistry, particularly for the clean-up and pre-concentration of analytes from complex matrices before instrumental analysis (e.g., HPLC, GC, LC-MS).
CN (Cyano) Phase Overview:
The CN (cyano) bonded phase in these cartridges is polar with moderate non-polar character, making it suitable for both normal phase and reversed phase applications, depending on the solvent system used.
Common Uses of Hi-Purit™ CN SPE Cartridges:
Sample Cleanup:
Removes interfering matrix components from biological, food, or environmental samples before analysis.
Moderately Polar Compound Retention:
Ideal for compounds with intermediate polarity—not too polar and not too non-polar.
Typical examples: steroids, vitamins, drugs, pesticides, and metabolites.
Normal Phase Applications:
Separates polar compounds using non-polar solvents.
CN phase offers more reproducibility and less water sensitivity than bare silica.