In analytical HPLC, maintaining sample integrity and preventing evaporation or contamination is crucial. Crimp caps:
Provide excellent seal integrity, especially for volatile solvents.
Are compatible with autosamplers, which pierce the septum to draw the sample.
Minimize sample evaporation and leaching of contaminants compared with screw caps.
Are available in various septum materials (e.g., PTFE/silicone, PTFE/red rubber) to suit different solvents and analytes.